Sarah Vine describes her historical past of being prescribed antidepressants after which having withdrawal issues (see Every day Mail article). She explains that antidepressants, in her view, cease the “metaphorical home falling down when you get the metaphorical builders in”.
Unsure whether or not the pandemic has actually elevated antidepressant prescribing (see Lancet Psychiatry letter). The difficulty about efficacy of antidepressants has probably not progressed since NICE produced its first despair guideline (see eletter: What does it imply to say that antidepressants have helped tens of millions of individuals around the world?). The Important Psychiatry Community (of which I’m a founding member) had a debate about this difficulty in 2003 (see one other eletter). There’s a real difficulty about bias in medical trials of antidepressants (see one more eletter).
All this was checked out in a BMJ editorial in 2004 (see one other eletter). The central difficulty is whether or not antidepressant trials conceal amplified placebo results and more moderen analysis has probably not taken this difficulty ahead (see earlier put up). Antidepressants could not work any higher than placebo. If that is true (which I feel it could be), it will have extraordinary implications for medical observe. So-called antidepressant efficacy could merely be as a result of placebo impact (see eg. my article).
